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Pink Angellou Carbon posted an update in the group
MT 30 – IJ (LEC) 3 years, 7 months ago This article by Rubattu and Volpe (2019) emphasizes the significance of natriuretic peptides in cardiovascular physiology, pathology, and in the diagnosis and treatment of cardiovascular diseases.
Since their discovery about twenty years ago, natriuretic peptides have been firmly established as crucial variables in the control of intravascular volume and cardiovascular hemostasis, and have been instrumental in the formation of the new area of cardiovascular endocrinology.
Natriuretic Peptides in the Cardiovascular System: Multifaceted Roles in Physiology, Pathology and Therapeutics – PubMedThe natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and …-
Atria and ventricles, respectively, release atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP). ANP decreases blood pressure and heart hypertrophy via endocrine and paracrine signaling. BNP operates locally to decrease ventricular fibrosis. -
Quantitative evaluation of circulating levels of cardiac natriuretic peptides has also been demonstrated to be essential for determining the severity of heart dysfunction. Plasma levels of ANP and BNP are both increased in individuals with cardiac dysfunction and heart failure. Plasma BNP levels correspond more closely with the degree of left ventricular failure.
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Plasma BNP levels correspond more closely with the degree of left ventricular failure. The use of BNP levels as a diagnostic, therapeutic, and prognostic marker of left ventricular failure has been solidly established by prior research.
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