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James Xavier L Tan posted an update in the group
(MT 30) Medical Histology – F (LAB) 2 years, 2 months ago JAMES XAVIER L. TAN
BMST – II
MT 30 LAB – FC. Connective Tissue
Connective Tissue
Connective tissues serve various functions including binding structures together, providing support and framework for organs and the body, storing fat, transporting substances, defending against disease, and aiding in tissue repair. They are distributed throughout the body. Connective tissues are characterized by a rich intercellular matrix with relatively sparse cell populations. While connective tissue cells are capable of reproduction, their rate is slower compared to epithelial cells. Most connective tissues are well vascularized, although exceptions exist. Various cell types inhabit connective tissue, with fibroblasts, macrophages, and mast cells being among the most prevalent. Types of connective tissue encompass loose connective tissue, adipose tissue, dense fibrous connective tissue, elastic connective tissue, cartilage, osseous tissue (bone), and blood.
Human blood smear
Blood transports oxygen and nutrients to all body parts, sustaining their functions. It conveys carbon dioxide and various waste products to the lungs, kidneys, and digestive system for elimination. Additionally, blood plays a role in immune defense by combating infections and facilitates the distribution of hormones throughout the body. Red blood cells, also known as erythrocytes, are responsible for carrying oxygen from the lungs to all parts of the body and transporting carbon dioxide back to the lungs for exhalation. They contain hemoglobin, a protein that binds oxygen. White blood cells, also called leukocytes, are essential components of the immune system. They help the body fight infections and diseases by attacking and destroying pathogens, such as bacteria, viruses, and other foreign invaders. Platelets, also known as thrombocytes, are small cell fragments found in the blood. They play a crucial role in blood clotting (hemostasis) by forming clots to stop bleeding when blood vessels are damaged. Additionally, they release substances that promote clotting and help repair damaged blood vessels.Yellow elastic tissue
Yellow elastic tissue, also known as elastic connective tissue, is a type of connective tissue characterized by its abundance of elastic fibers. These fibers provide the tissue with elasticity and resilience, allowing it to stretch and recoil while maintaining its shape. Yellow elastic tissue is composed primarily of elastic fibers, which are made up of the protein elastin. These fibers are arranged in a branching network within a matrix of ground substance and fibroblast cells. The elastic fibers appear yellowish under a microscope due to the staining methods used to visualize them. The primary function of yellow elastic tissue is to provide elasticity and recoil to various organs and tissues throughout the body. It is found in structures that require stretching and recoiling capabilities, such as the skin, lungs, blood vessels, and certain ligaments. In the skin, yellow elastic tissue allows it to stretch and return to its original shape after stretching, contributing to its overall elasticity. In the lungs, elastic tissue aids in the expansion and contraction of lung tissue during breathing. Similarly, in blood vessels, elastic tissue helps maintain blood pressure by allowing arteries to expand and recoil with each heartbeat. Overall, yellow elastic tissue plays a crucial role in maintaining the structural integrity and functionality of various tissues and organs in the body.
Bone marrow smear
Bone marrow is a spongy tissue found inside bones, primarily in the cavities of long bones such as the femur and tibia, as well as the pelvic bones, sternum, and vertebrae. It consists of two main types: red bone marrow and yellow bone marrow. Red bone marrow is highly vascular and contains hematopoietic stem cells, which are responsible for producing all types of blood cells, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). Red bone marrow appears reddish due to its rich blood supply and active blood cell production. Red bone marrow is the primary site of hematopoiesis, the process of blood cell formation. Hematopoietic stem cells within the red marrow give rise to various types of blood cells, including red blood cells, white blood cells, and platelets. These blood cells are essential for oxygen transport, immune defense, and blood clotting, respectively. On the other hand, yellow bone marrow is composed mainly of adipocytes (fat cells) and is less vascular compared to red bone marrow. It serves primarily as a storage site for fat cells and contains fewer hematopoietic stem cells. Yellow bone marrow can convert to red bone marrow in response to certain physiological conditions, such as increased demand for blood cell production. Yellow bone marrow serves as a site for energy storage in the form of adipocytes and triglycerides. During periods of increased energy demand or starvation, the stored fat can be mobilized and utilized by the body for energy production.
Human spleen
The spleen is an organ located in the upper left abdomen, beneath the rib cage and next to the stomach. It is part of the lymphatic system and serves several important functions in the body. The spleen is a soft, spongy organ that is highly vascularized and contains two main types of tissue: white pulp and red pulp. White pulp consists of lymphocytes (a type of white blood cell) and is involved in immune function. It contains clusters of lymphoid tissue called lymphoid nodules, where immune cells are activated and respond to pathogens. On the other hand, red pulp is made up of a network of sinuses filled with blood and splenic cords composed of various cell types, including red blood cells, macrophages, and platelets. Red pulp functions primarily in filtering the blood and removing old or damaged red blood cells. The spleen plays a crucial role in the body’s immune response by filtering the blood and trapping pathogens such as bacteria, viruses, and foreign particles. Lymphocytes in the white pulp respond to these pathogens by initiating an immune response, including the production of antibodies to help fight infection. Red pulp serves as a blood filter, removing old or damaged red blood cells, as well as foreign particles and debris, from the circulation. Macrophages in the spleen engulf and break down these cells and particles, helping to maintain the quality of circulating blood.
References:
https://training.seer.cancer.gov/anatomy/cells_tissues_membranes/tissues/connective.html
https://kidshealth.org/en/teens/blood.html#:~:text=Blood%20brings%20oxygen%20and%20nutrients,carries%20hormones%20around%20the%20body.
https://www.sciencedirect.com/topics/medicine-and-dentistry/elastic-fiber
https://my.clevelandclinic.org/health/body/22818-bone-marrow
https://my.clevelandclinic.org/health/body/21567-spleen
https://www.kenhub.com/en/library/anatomy/the-spleen