Vein tissue is generally thinner and less muscular compared to arteries. It is made up of three layers, but the middle layer, which contains smooth muscle and elastic fibers, is much thinner. This gives veins less strength and elasticity, but it also allows them to be more flexible and able to hold larger volumes of blood. The inner lining, called the endothelium, is smooth to help blood flow easily. Veins also have valves made from tissue folds, which prevent blood from flowing backward. Overall, vein tissue is soft, collapsible, and adapted for low-pressure blood flow back to the heart.

Under LPO (10x), the vein shows a thinner tunica media compared to the artery, with a wider lumen and less smooth muscle. This structure allows veins to carry blood at lower pressure and accommodate more volume. What a site to see, indeed!🥹

Under LPO (10x), the artery shows a thick wall, the vein a wide lumen with thin muscle, and the nerve stands out with its solid structure.