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The reproductive system ensures the survival of the species. Other systems in the body, such as the endocrine and urinary systems, work continuously to maintain homeostasis for the survival of the individual. An individual may live a long, healthy, and happy life without producing offspring, but if the species is to continue, at least some individuals must produce offspring.
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At any stage of development, follicle degeneration (atresia) can occur. The granulosa cells die, and the oocyte degenerates as a result. The basement membrane that separates the oocyte from the granulosa cells frequently thickens to form the glassy membrane. The granulosa cells are replaced by fibrous material.