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  • Christian Pavillar Edulan posted an update in the group Group logo of Histology Art (MT 30 - J)Histology Art (MT 30 – J) 3 years, 7 months ago

    The kidneys, ureters, urinary bladder, and urethra make up the urinary system. Urine generation, storage, and excretion are its primary functions.

    Kidneys serve numerous purposes:
    Excretion – elimination of water-soluble metabolic wastes and foreign substances as urine
    Regulation – maintain an appropriate fluid volume and concentrations of various electrolytes in the body fluids, maintain normal blood pressure, and maintain the pH of blood
    Endocrine – secretion of hormones
    Renin – regulation of blood pressure
    Erythropoietin – stimulates production of red blood cells
    Vitamin D – regulation of calcium levels

    The urinary bladder is a muscle sac that retains urine and allows for infrequent, deliberate urination. It contains a thick layer of smooth muscle and is bordered with transitional epithelium (urothelium).

    The ureters are fibromuscular tubes that transfer urine from the kidney to the bladder by peristalsis. Transitional epithelium lines it, much like the bladder (urothelium).

    • Kidney

      It filter blood and produce urine. Unlike the human kidney which is multilobed (10 to 12 lobes) separated by renal columns (cortical tissue that extends alongside the margin of pyramids in the medulla), the monkey kidney is unilobular.

      Cortex – darker outer region.
      Renal Corpuscles – spherical structures that form ultrafiltrate from blood.
      Cortical Labyrinths – regions between renal corpuscles and medullary rays that contain proximal and distal convoluted tubules.
      Medullary Rays – projections of tubules between the cortex and medulla that contains straight tubules and collecting ducts.
      Medulla – lighter inner region.
      Pyramids – equal to the number of lobes and form conical structures whose base faces the cortex and their apex form the renal papilla. Urine passes through the minor calyx which is cup-shaped structure that is an extension of the renal pelvis.
      Renal Pelvis – funnel-shaped origin of the ureter.
      Arcuate Arteries – branches of interlobular arteries that form an arcade over the pyramids at the junction of the cortex and medulla.
      Hilum – concave surface with a deep fissure in which vessels enter and exit the kidney.

      • Ureter
        It transports urine from the kidney to the bladder. It is lined with an epithelium that is impermeable to water and ions. Peristaltic contraction of the smooth muscle moves urine from the kidney to the bladder.

        Transitional Epithelium (Urothelium) – consists of two to three cell layers in the upper ureter with up to ten cell layers near the bladder
        Umbrella Cells – upper layer of cells that change shape depending on the distention of the ureter (extended)
        Lamina Propria – thick layer of dense irregular connective tissue rich in collagen and elastic fibers
        Muscularis Externa – irregular arrangement of smooth muscle in two layers (inner longitudinal and outer circular) in the upper ureter or three layers (inner longitudinal, middle circular and outer longitudinal) near the bladder
        Adventitia – loose connective tissue with blood vessels, nerves and adipose cells

        • Bladder

          It is an expandable vessel for the storage of urine. It is lined with an epithelium that is impermeable to water and ions. Like the ureters, the bladder is composed of four concentric layers.

          Transitional Epithelium (Urothelium) – consists of three to five cell layers.
          Umbrella Cells – the upper layer of cells that change shape depending on the distention of the bladder.
          Lamina Propria – thick layer of dense irregular connective tissue rich in collagen and elastic fibers.
          Muscularis Externa – irregular arranged smooth muscle that forms an inner longitudinal, middle circular and outer longitudinal layers.
          Outer Layer of Connective Tissue – most of the bladder is covered externally by adventitia with parts of its superior surface covered by serosa of the peritoneum.
          Adventitia – loose connective tissue with blood vessels, nerves and adipose cells.
          Serosa – composed of a surface layer of mesothelium supported by loose irregular connective tissue.

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