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  • Dyanne Nicole Zerna posted an update in the group Group logo of MT 30 - GH (Lec)MT 30 – GH (Lec) 4 years, 4 months ago

    Hey there! How is everyone doing? Here is an informative article that I found to help you know more about your sinoatrial (SA) node. I hope this helps! :>

    Kindly check the comment section for more information about the article. Thanks!

    • This article by Melanie C. Bois, Cecilia W. Wu, Christine M. MArtinez, et al., focuses on uncovering more information on the anatomy of the SA node. It was mentioned that understanding of the histologic makeup of the sinoatrial (SA) node is characterized by small research with unequally distributed ages and subjective estimates of nodal morphology, making it hard to determine what comprises the SA node. A number of SA nodes were graphically examined to assess their histologic makeup. Results showed that the sinoatrial (SA) node collagen somehow does not grow over age or correlate with body mass index (BMI). It means that age does not have anything to do with the increase of the SA node collagen, nor does it connect with one’s BMI. Aside from that, it also revealed that the SA nodes with collagen greater than 50% (per nodal area) are aberrant throughout the age and gender range. It means that it is abnormal in terms of age and gender. Additionally, results showed that Nodal fat content is roughly related to body mass index (BMI).
      The heart has tiny parts that are not given much attention, one of which is the sinoatrial (SA) node. It is undeniable that the SA node is just a tiny part of the circulatory system, but it surely helps the system and our body to function properly —especially our hearts. I have realized that there are still things that we are yet to discover about the SA node. Overall, I could honestly say that the article has been very informative and helpful, especially to me, who is now a sophomore MedTech student. Other premed students like me could also attest that we have come across SA nodes in some of our major subjects, but the additional information that were revealed indeed increased our knowledge about the said topic. With that, I could infer that there is a need to dig deeper into specific details of our lessons. It is because it could surely add to our limited knowledge about certain topics and could even be a way for us to inform others about such.
        • Reference:
          Bois MC, Wu CW, Martinez CM, Castonguay MC, Jenkins SM, Maleszewski JJ. Age-related histologic features of the sinoatrial node from normal human hearts during the first 10 decades of life: a study of 200 cases. Cardiovasc Pathol. 2021 May-Jun;52:107327. doi: 10.1016/j.carpath.2021.107327. Epub 2021 Feb 23. PMID: 33636251.

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