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  • Angelyn V. Duhig posted an update in the group Group logo of MT 30 - IJ (LEC)MT 30 – IJ (LEC) 4 years, 1 month ago

    In the circulatory system, blood vessels are critical components, as they are responsible for the dynamic transfer of materials and blood products to and from every cell in the body.
    The vascular network originates at the heart’s outlets, travels throughout the body, and returns to the heart’s primary venous inlets to complete the cycle.
    This intricate vascular highway is responsible for transporting blood cells, nutrients, oxygen, and pharmacological substances to and from the tissues.
    In the same way as blood arteries move material toward the tissue, they also facilitate the elimination of cellular byproducts, carbon dioxide, and harmful substances from the tissues.
    The vascular system is divided into two categories according to its histological structure: the macrovasculature and the microvasculature.
    Generally speaking, the macrovasculature refers to any vessel that can be seen with the naked eye, whereas the microvasculature refers to vessels that are smaller than 100 microns in size.

    • The most frequent method of histological visualization of blood vessels is with regular hematoxylin and eosin (H&E) staining.

      The heart and blood vessels make up the cardiovascular system (arteries, arterioles, capillaries, venules, veins). This system transports oxygenated blood from the heart to the tissues while returning deoxygenated blood from the tissues to the heart and lungs. Both the heart and the blood vessels have three histological layers:

      Endothelial layer – an epithelial tissue composed of simple squamous (endothelial) cells. This layer is known as the endocardium in the heart.

      Muscular layer- Smooth muscle in the blood arteries and cardiac muscle (myocardium) in the heart.

      External layer – consists of loose connective tissue (adventitia) in blood vessels and a squamous epithelial (mesothelial) layer in the heart (epicardium). The epicardium is bordered by the second layer of mesothelial cells known as the pericardium.

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