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  • Miguel Gatsi posted an update in the group Group logo of Microscopic Photos of Reproductive System Tissue SlidesMicroscopic Photos of Reproductive System Tissue Slides 4 years ago

    Histology of the uterus
    The uterus has three layers: mucosa (endometrium), muscularis (myometrium) and serosa/adventitia (perimetrium). The endometrium (uterine mucous membrane) is lined with simple columnar epithelium (lamina epithelialis) and contains numerous tubular glands.
    • The uterus undergoes cyclic changes during the menstrual cycle divided into proliferative, secretory and menstrual phases. This specimen is from the proliferative phase.

      The uterine wall is composed of three layers:

      Endometrium – specialized mucosa that undergoes marked changes during the menstrual cycle.
      Functional Layer (or stratum functionalis) – upper two thirds that regenerates from cells in the basal layer under the influence of estrogen.
      Simple Columnar Epithelium – epithelial cells remaining from the bases of glands rapidly proliferate and migrate to restore the surface epithelium.
      Endometrial Stroma – cells proliferate and secrete collagen and ground substance to restore the lamina propria.
      Uterine Glands – surface epithelium invaginates into the stroma to form new glands.
      The glands are straight (or slightly wavy) and have narrow lumens.
      Very little secretion.
      Basal Layer (or stratum basalis) – lower third of the mucosa that is retained during menstruation and regenerates the functional layer.

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