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Kyra Kris Lequin posted an update in the group
MT30-Histology Art AB 4 years, 5 months ago Research Discoveries regarding the Histology of the Integumentary System.
Article: The structure of normal skin and morphology of atopic eczema.
https://www.jidonline.org/article/S0022-202X(15)44832-8/pdf-
Epidermis and dermis alterations in atopic eczema vary according to the nature of the clinical lesion. Vesicular areas demonstrated substantial intercellular edema with the production of so-called spongiotic vesicles, varied epidermal hyperplasia, typically of a psoriasiform type, and inflammatory infiltration of lymphocytes and lymphoblasts.-
In some cases, an array of radially arranged purple lines suggested reduplication of the basement membrane, whereas in others, sclerosis and thickening of the basement membrane zone were visible. The vesicular lesions exhibited minor dermal edema. Macrophages harboring melanin granules were found in the whole dermis.
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Previous reports of edema of the venular endothelial cells in atopic eczema have been expanded to include endothelial cell hypertrophy, basement membrane reduplication and homogenous thickness, and pericyte hypertrophy in the acute and lichenified phases of the disease. In the lack of an inflammatory infiltrate in lesional skin, venule changes may indicate either a systemic underlying illness or limited involvement.
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